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It is a disease where the body's immune system attacks the cells that make insulin.
Insulin helps sugar (glucose) get into your cells so it can be used as energy.
Our studies illustrate how islet transcription factors interact functionally with the epigenome and provide systematic evidence that the dysregulation of islet enhancers is relevant to the mechanisms underlying type 2 diabetes.
Type 1 diabetes is one of the most common and serious long-term diseases in children.
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T1DM used to be called childhood diabetes or insulin-dependent diabetes.
The aims of EFSD are to encourage and support groundbreaking diabetes research and to promote the next generation of leading diabetes researchers.
more Diabetologia is the Journal of the EASD and publishes original clinical, translational and experimental research within the field of diabetes.
We identify genomic sequences that are targeted by islet transcription factors to drive islet-specific gene activity and show that most such sequences reside in clusters of enhancers that form physical three-dimensional chromatin domains.
We find that sequence variants associated with type 2 diabetes and fasting glycemia are enriched in these clustered islet enhancers and identify trait-associated variants that disrupt DNA binding and islet enhancer activity.
Further, we establish a correlation between relative abundance of spp.
A monthly newsletter updating the businesses and people of Cork about the events and activities happening in our wonderful city centre. Three day UNESCO conference in Cork comes to a close Mayors and representatives of cities worldwide, education experts, UN representatives, the private sector, and regional, international and civil society organisations from 92 countries assembled in Cork over the last three days. Ballyvolane Fire Station goes even greener and saves more money Solo Energy has teamed up with Cork City Council to install a groundbreaking energy storage system at Ballyvolane Fire Station. The city's parking spots to go green this Friday Artists, designers and ordinary people will transform paid parking places in Cork into temporary public parks this Friday as part as part of Park (ing) Day, an annual worldwide event. Building Facade Improvement Grant Schemes 2017- Blackpool & South Douglas Street Area The 2017 Building Facade Improvement Grant Scheme (formerly known as the Painting Grant Scheme) is coming to a close. Latest census results show that Cork city has seen the biggest increase in workforce of all the Irish cities The Lord Mayor of Cork, Cllr Tony Fitzgerald has welcomed the latest census results which showed that Cork city has seen the biggest increase in workforce of all the Irish cities. Lots of festivals going on this September in Cork City! The BBC broadcaster Peter Day recently travelled to Cork to find out what life is really like in a country just recently realised from the constraints of an EU bailout. ITS Ireland Award “Recognising Excellence in Deploying ITS” for 2013 Cork City Council was selected to receive the ITS Ireland Award “Recognising Excellence in Deploying ITS” for 2013 which Cork shared with Kildare Co. Cork was voted the winner in the “The Great Town” category by members of the Academy of Urbanism. More On Thursday, 3rd October, 2013, the Lord Mayor of Cork announced details in City Hall of the Chanticleer Choral Workshop and Concert being given by the members of Chanticleer. Lord Mayor announces details of Cork - Towards an Age-Friendly City Conference On Tuesday 1 October 2013 (International Day of Older Persons), the Lord Mayor of Cork Cllr.… continue reading »